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2-OXO-PCE, also known as 2-oxo-1-phenylcyclohexanone, is a synthetic stimulant compound that belongs to the phenethylamine class. This substance has been subject to research and investigation due to its potential use as a designer drug or club drug.

Chemical Structure

The chemical structure of 2-OXO-PCE consists of an aromatic ring system with a cyclohexanone moiety attached at the 2-position. The molecule features a functional group at the phenyl ring, which is responsible for its pharmacological properties.

Chemical Structure of 2-OXO-PCE

Mechanism of Action

The mechanism of action of 2-OXO-PCE is not fully understood. However, it is thought to bind to specific receptors in the brain, potentially stimulating the release of dopamine and serotonin. These brain chemicals are associated with pleasure and reward, contributing to the psychoactive effects of 2-OXO-PCE.

Legal Status

2-OXO-PCE is not listed as a controlled substance under international drug conventions. Therefore, its legal status varies by country and region. Some jurisdictions classify it as a designer drug or research chemical, while others have implemented laws to restrict its production and distribution. It is essential to check the current legal status of 2-OXO-PCE in relevant jurisdictions.

Side Effects and Risks

The use of 2-OXO-PCE has been associated with various side effects and risks. These may include:

– Psychological Effects: Users may experience changes in mood, such as increased energy, euphoria, and feelings of well-being. However, these can be accompanied by irritability, anxiety, and agitation.

– Physical Effects: 2-OXO-PCE may cause increased heart rate, blood pressure, and body temperature. Users may also experience dry mouth, increased heart rate, and tremors.

– Adverse Reactions: In rare cases, the use of 2-OXO-PCE has been linked to elevated heart rate and blood pressure, anxiety, hallucinations, and seizures.

– Dependence and Tolerance: Regular use of 2-OXO-PCE can lead to the development of tolerance, where users require higher doses to achieve the desired effects. It may also lead to dependence, with withdrawal symptoms upon cessation of use.


2-OXO-PCE is a synthetic stimulant compound that has gained attention for its psychoactive properties. While its mechanism of action is not fully understood, it is thought to be associated with dopamine and serotonin release in the brain. Its legal status varies by country, and its side effects and risks should be carefully evaluated before considering its use.

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