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5-Br-DMT, also known as 5-MeO-DMT or bufotenin, is a psychoactive compound found in the Bufo Alvarius toad. It belongs to a class of drugs known as tryptamine derivatives and is similar to other psychedelic compounds like psilocybin and LSD.

Chemistry and Structure

5-Br-DMT is a derivative of DMT, which is naturally produced by various plants and animals. DMT is a monoamine alkaloid that has a molecular structure similar to serotonin. 5-Bromo-DMT is obtained by substituting bromine atoms for the hydrogen atoms on the DMT molecule.


5-Bromo-DMT acts as a selective serotonin 2A receptor agonist, meaning it binds to a specific serotonin receptor in the brain known as serotonin 2A receptors. This binding triggers a release of serotonin and other neurotransmitters, leading to altered states of consciousness.


When ingested, 5-Bromo-DMT produces a wide range of effects, including:

1. Visual hallucinations: Users often report seeing vivid patterns and colors, geometric shapes, and distortions in their vision.

2. Enhanced sensory experiences: Users may experience a heightened sense of perception, including enhanced hearing, taste, and touch.

3. Anxiety reduction: Some users report that 5-Bromo-DMT helps them manage anxiety and reduces feelings of fear.

4. Increased empathy: Users often report feeling a greater sense of empathy towards others, which can lead to increased feelings of interconnectedness.

5. Spiritual experiences: Many users report having profound spiritual experiences, including feelings of interconnectedness, unity, and cosmic consciousness.

6. Enhanced creativity: Some users report increased creativity and problem-solving abilities under the influence of 5-Bromo-DMT.

Use and Safety

5-Bromo-DMT is not approved for medical or recreational use and is illegal in most countries. Its use carries potential risks, including hallucinations, altered perception of reality, and the potential for psychological harm.

The use of 5-Bromo-DMT should only be considered by those who are aware of the potential risks involved and are prepared to manage them responsibly. It is important to only consume 5-Bromo-DMT under the supervision of experienced practitioners or in controlled settings, such as designated research facilities or legal contexts.


5-Bromo-DMT is a psychoactive compound that belongs to the class of tryptamine derivatives. It is derived from the Bufo Alvarius toad and is known for its hallucinogenic effects. While 5-Bromo-DMT has been explored for various therapeutic applications, its safety and legal status remain a concern. It is essential to approach the use of 5-Bromo-DMT with caution and respect its potential risks and benefits.

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