S-Isomer Ketamine


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S-Isomer Ketamine

S-Isomer Ketamine, also known as Special K or K, is a dissociative anesthetic that is commonly used for anesthesia during medical procedures. It is a synthetic compound that belongs to the phencyclidine (PCP) class of drugs. Ketamine works by blocking certain receptors in the brain, resulting in dissociative effects such as hallucinations and an altered perception of reality.

Structure and Properties

Ketamine is composed of two enantiomers, which are mirror-image forms of the same molecule. The two enantiomers of ketamine are known as the R- and S-enantiomers. The S-isomer of ketamine is the most common form of the drug used in medical settings.

The S-isomer ketamine has a chemical structure that consists of a cyclohexane ring connected to another ring containing nitrogen and oxygen. This structure gives it its unique pharmacological properties.

Pharmacology and Effects

The S-enantiomer of ketamine has greater affinity for certain receptors in the brain, making it ideal for medical use. It primarily binds to the NMDA receptor, resulting in its anesthetic and hallucinogenic effects. At lower doses, ketamine can produce feelings of euphoria and relaxation, but higher doses can lead to more severe dissociative effects.

Ketamine is often used for anesthesia in surgical and other medical procedures due to its fast-acting nature and short duration of action. It also has analgesic properties and can reduce pain perception. However, it is important to note that ketamine should be used under the supervision of medical professionals to ensure its safe and effective administration.

Side Effects and Risks

While ketamine may be effective for certain medical purposes, it also comes with potential risks and side effects. Common side effects include dizziness, nausea, hallucinations, and disorientation. It can also cause psychological effects, such as anxiety, depression, and addiction.

Ketamine use also carries the risk of abuse and misuse, especially in recreational settings. Overdose or prolonged use can result in respiratory depression, unconsciousness, and even death. It is important to use ketamine only as prescribed by a healthcare professional and to avoid recreational use or abuse.


The S-enantiomer of ketamine is the more common form of the drug used in medical settings. It has a unique chemical structure and binds to specific receptors in the brain, resulting in anesthesia, analgesic effects, and hallucinogenic effects. While it may be effective in certain medical settings, ketamine use should be approached with caution and under the supervision of healthcare professionals.

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