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4-Chlorophenylpiperazine Hydrochloride


4-Chlorophenylpiperazine Hydrochloride (4-CI-PVP HCL) is a synthetic compound that belongs to the phenylpiperazine class. It is a hydrochloride salt form of the molecule 4-chlorophenylpiperazine. 4-CI-PVP HCL is a research chemical that has gained attention due to its potential applications in various fields, including neuroscience and psychology.

Chemical Composition

The chemical formula for 4-CI-PVP HCL is C14H21NO2HCl. It consists of a phenylpiperazine core structure, featuring a phenyl ring connected to an piperazine ring at one of its nitrogen atoms. The HCl group is attached to another nitrogen atom on the piperazine ring, creating a hydrochloride salt.

Physical Properties

4-CI-PVP HCL has a slightly off-white to beige-colored powder appearance. It is soluble in water and ethanol but less soluble in acetonitrile. The compound is stable under normal storage conditions, but exposure to light and heat can degrade its quality.

Chemical Properties

4-CI-PVP HCL exhibits various chemical properties that have contributed to its interest in research. It undergoes deprotonation to form a neutral base, which can enhance its binding affinity with receptors and enzymes. The compound also undergoes oxidation, which can generate reactive oxygen species, potentially contributing to its toxicological effects.

Pharmacological Effects

4-CI-PVP HCL is primarily known for its potential as a psychostimulant. It has been shown to bind to serotonin and dopamine receptors in the brain, which can result in increased alertness, euphoria, and feelings of pleasure. However, its pharmacological profile is not fully understood, and more research is needed to fully understand its mechanism of action and potential therapeutic applications.

Legal Status

4-CI-PVP HCL is a research chemical, which means it is intended for laboratory use only and has not been approved for medical or recreational use by regulatory bodies. Its legal status varies by country, and it is important to familiarize yourself with the laws and regulations governing the possession and use of research chemicals in your area.

Safety Precautions

Handling 4-CI-PVP HCL requires caution due to its potential toxicity. Proper personal protective equipment, such as gloves and goggles, should be worn to minimize exposure to its powdered form. Inhalation of its dust or mist should be avoided, and the substance should be stored in a secure location out of reach of children and pets.


4-CI-PVP HCL is a synthetic compound belonging to the phenylpiperazine class. It has gained attention for its pharmacological effects and potential applications in various fields, including neuroscience and psychology. However, its legal status and safety concerns should be carefully considered before engaging in any research or experimentation involving this compound.

Additional information


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